The effects of sub-chronic administration of an aqueous extract of Ficus bengalensis stem bark on hematological and biochemical parameters in rats with streptozotocin (STZ)-induced diabetes were evaluated. The possible protective effect of the F. bengalensis (500 mg/kg of body weight per day) extract on STZ-induced changes was evaluated over 12 weeks. The parameters evaluated were plasma proteins, including total protein albumin and globulin, non-protein nitrogenous substances, including urea, uric acid, and creatinine, and hematological indices, including total hemoglobin content, erythrocytes, leucocytes, and platelets counts. The aqueous extract had a significant (P < 0.05) protective effect against STZ-induced changes in terms of the markers of protein metabolism and hematological indices. Furthermore, increases in levels of non-protein nitrogenous substances were normalized in response to the administration of the extract. Thus, the aqueous extract of F. bengalensis had a significant protective effect on STZ-induced changes to biochemical and hematological parameters in the diabetic rats.
Ficus bengalensis, streptozotocin, non-protein nitrogenous substances, hematological indices
GAYATHRI, MAHALINGAM and KANNABIRAN, KRISHNAN
"The Effects of Oral Administration of an Aqueous Extract of Ficus bengalensis Stem Bark on Some Hematological and Biochemical Parameters in Rats with Streptozotocin-Induced Diabetes,"
Turkish Journal of Biology: Vol. 33:
1, Article 2.
Available at: https://journals.tubitak.gov.tr/biology/vol33/iss1/2