•  
  •  
 

Turkish Journal of Biology

[8-14C] Inosine Metabolism by Streptomyces yokosukanensis ATCC 25520

Muhsin KONUK

DOI

-

Abstract

[8-14C] inosine metabolism by Streptomyces yokosukanensis ATCC 25520, which is one of the producers of nebularine (a purine riboside antibiotic), was investigated in vitro. Inosine was shown not to be a precursor of nebularine (the conversion figure was around 0.29%), and most of the riboside presented (~ 80%) was metabolized along other metabolic routes. In this study fourteen [14C]-labelled purine bases, ribosides and ribotides were identified. They were; purine xathine, guanine, adenine, hypoxanthine, nebularine, xanthosine, guanosine, adenosine, inosine, AMP, IMP, GMP, and GDP.

Keywords

Streptomyces yokosukanensis, nebularine, purine metabolism, inosine

First Page

235

Last Page

239

This document is currently not available here.

Share

COinS