•  
  •  
 

Turkish Journal of Electrical Engineering and Computer Sciences

DOI

10.3906/elk-1803-197

Abstract

This study aims to elucidate the production mechanism of cytokine-like formations secreted from T cells and similar cells by electromagnetic modeling techniques. Three Hertz dipole antennas polarized in arbitrary directions were placed without touching each other at the center of spherical T-cell models to test the Canbay hypothesis about the formation mechanism of cytokines (CHAFMOC) on T-cell surfaces. A dielectrophoretic force field was created within the gelatin layer of the T-cell model. The prepared control and electromagnetically stimulated T-cell model samples were incubated in water in a glass container in a Faraday cage for the specified period and then photographed. At the end of the experiments, cytokine-like formations were observed in the samples, depending on their contents. The results of these experiments, carried out in accordance with the CHAFMOC, show that a dielectrophoretic force is the main cause of the cytokine formation and secretion mechanism in the outer layers of rough T-cell models. Given these results, new approaches and developments may be expected to better our understanding of the immune system in the subjects of cell science, pharmacology, and bioengineering.

Keywords

Cytokine, T cell, dielectrophoretic force, Hertz dipole, immune system

First Page

37

Last Page

45

Download

Share

COinS