\alpha -Difluoromethylornithine (DFMO), a specific enzyme activated inhibitor of ornithine decarboxylase (ODC), significantly inhibited the mycelial growth of the fungus Macrophomina phaseoli (Tassi) Goidanich. Putrescine (Put), when added to the nutrient medium at a concentration of 0.25 mM, decreased the inhibitory effect of DFMO. These results suggest that polyamines (PAs) are essential for the growth of fungi and that DFMO is applicable to the alleviation or prevention of crop losses due to phytopathogenic fungi.
ÜNSAL, NARÇIN PALAVAN; ÇOTUK, AYŞIN; and MARTINI, YEŞİM KALAÇ (2002) "\alpha -Difluoromethylornithine Inhibits the Growth of Fungus Macrophomina phaseoli," Turkish Journal of Botany: Vol. 26: No. 1, Article 6. Available at: https://journals.tubitak.gov.tr/botany/vol26/iss1/6