•  
  •  
 

Turkish Journal of Biology

Abstract

Background/aim: LUNGBANK was established as a pioneering biorepository dedicated to lung cancer. Designed for streamlined biospecimens handling, it employs high-volume technologies to secure high-quality samples. Fortified with robust data management, LUNGBANK efficiently integrates diverse datasets. This strategic infrastructure positions LUNGBANK as more than a biospecimens repository; it operates as a sophisticated platform for advanced lung cancer research, amplifying the potential for meaningful discoveries.Materials and methods: LUNGBANK is intricately designed to streamline the collection, transfer, storage, and processing of biospecimens, employing high-volume technologies to ensure the acquisition of high-quality biological specimens. The system is fortified with robust data management protocols, facilitating efficient integration of diverse datasets. This strategic infrastructure ensures that LUNGBANK not only serves as a repository of biospecimens but also operates as a sophisticated platform for advanced lung cancer research.Results: LUNGBANK plays an essential role in furnishing a rich collection of biospecimens essential for unraveling the molecules and mechanisms linked to lung cancer. Rigorous standard operating procedures guided the meticulous collection of biospecimens, subjecting them to stringent quality control measures before inclusion in the study. Moreover, LUNGBANK has proven valuable in the establishment of patient-derived systems. The incorporation of cutting-edge technologies guarantees the acquisition of top-tier data, thereby amplifying the likelihood of substantial breakthroughs in both contemporary translational research and traditional histological evaluations.Conclusion: The establishment of LUNGBANK marks a significant stride towards addressing the pressing need for effective diagnostic and therapeutic systems in lung cancer research. By facilitating the collection and analysis of high-quality biospecimens, LUNGBANK serves as a valuable resource for unraveling the molecular intricacies of lung cancer initiation and progression. This comprehensive system not only supports Project LUNGMARK but also contributes to the broader landscape of personalized medicine, tailoring interventions to the specific needs of lung cancer patients.

Author ORCID Identifier

DİLEK DEMİRCAN ÇEKER: 0009-0005-2913-4410

VOLKAN BAYSUNGUR: 0000-0003-1053-1051

SERDAR EVMAN: 0000-0002-1672-966X

İLKER KOLBAŞ: 0000-0003-1656-9595

ABDURRAHİM GÖRDEBİL: 0000-0002-4915-0830

SİNEM NALBANTOĞLU: 0000-0002-7067-6220

YUSUF TAMBAĞ: 0009-0005-6404-8630

ÖMER KAÇAR: 0000-0002-5402-2809

AHMET MİDİ: 0000-0002-6197-7654

HATİCE ASLANOĞLU: 0000-0002-1772-625X

NÜLÜFER KARA: 0009-0005-3809-1096

NİLGÜN ALGAN: 0009-0001-0026-4925

AYBERK BOYACIOĞLU: 0000-0002-1513-201X

BETÜL KARADEMİR YILMAZ: 0000-0003-1762-0284

ALİ ŞAHİN: 0000-0001-5594-1551

HİVDA ÜLBEĞİ POLAT: 0000-0001-8424-6849

ABİDİN ŞEHİTOĞULLARI: 0000-0002-4897-4205

ALİ ÇIBIKDİKEN: 0000-0003-4553-8202

MÜCAHİT BÜYÜKYILMAZ: 0009-0002-0117-2886

İBRAHİM AYDİLEK: 0000-0001-8037-8625

ABDULKERİM ENEŞ: 0009-0004-2637-4227

SEVDE KÜÇÜKER: 0009-0002-4162-439X

FATİH KARAKAYA: 0000-0003-2667-3724

İHSAN BOYACI: 0000-0001-7369-0426

MAHMUT GÜMÜŞ: 0000-0003-1899-0455

ONUR ŞENOL: 0000-0002-0252-396X

MERVE ÖZTUĞ: 0000-0002-6287-2774

EVREN SABAN: 0000-0002-1968-1470

ÖMER SOYSAL: 0000-0002-8832-9171

NUR BÜYÜKPINARBAŞILI: 0000-0002-1784-6665

AKİF TURNA: 0000-0003-3229-830X

MEHMET GÜNLÜOĞLU: 0000-0002-6952-3470

ASLI ÇAKIR: 0000-0003-0128-6947

ŞABAN TEKİN: 0000-0003-2641-6293

UYGAR TAZEBAY: 0000-0003-1999-8213

ABDULLAH KARADAĞ: 0000-0003-0969-7038

DOI

10.55730/1300-0152.2696

Keywords

Biobank, Biorepository, integrative multiomics, Lung cancer, P-medicine

First Page

203

Last Page

217

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Download

Included in

Biology Commons

Share

COinS