Turkish Journal of Biology
Abstract
Mitochondria are organelles that serve as the powerhouses for cellular bioenergetics in eukaryotic cells. It is responsible for mitochondrial adenosine triphosphate (ATP) generation, cell signaling and activity, calcium balance, cell survival, proliferation, apoptosis, and autophagy. Mitochondrial transplantation is a promising disease therapy that involves the recovery of mitochondrial dysfunction using isolated functioning mitochondria. The objective of the present article is to provide current knowledge on natural mitochondrial transfer processes, in vitro and in vivo applications of mitochondrial transplantation, clinical trials, and challenges associated with mitochondrial transplantation.
DOI
10.55730/1300-0152.2665
Keywords
Mitochondria, mitochondrial transplantation, mitochondrial transfer
First Page
301
Last Page
312
Recommended Citation
KUBAT, GÖKHAN BURÇİN
(2023)
"Mitochondrial transplantation and transfer: The promising method for diseases,"
Turkish Journal of Biology: Vol. 47:
No.
5, Article 2.
https://doi.org/10.55730/1300-0152.2665
Available at:
https://journals.tubitak.gov.tr/biology/vol47/iss5/2