Turkish Journal of Biology
DOI
10.55730/1300-0152.2658
Abstract
Background/aim: The novel field of nanomaterials allows infinite possibilities in order to create antioxidant therapies. The present review is aimed to describe the state of art concerning on nanomaterials and their effects on reactive oxygen species (ROS) production. A wide range of nanoparticles has been designed for this purpose, and each one possesses some particular characteristics which allow these significant antioxidant results. Several in vivo and in vitro works state the ability of these nanoparticles to mimic the redox systems of the cells, and thus, the potential role of nanoparticles as antioxidant treatment for several diseases. Materials and methods: This paper was written after a review of the articles published on the field, using the "PubMed" and "Research Gate" databases. Results: The main types of nanoparticles are listed and explained below, offering a global vision of the field with great interest for research. Antitumor chemo- and radiotherapies have been found to improve efficacy by enhancing the selectivity of cytocidal effects and minimizing systemic adverse effects when such materials are used. Furthermore, catalytic nanomaterials can execute energy-free antioxidant cycles that scavenge the most harmful reactive oxygen species via SOD- and catalase-like activities. Conclusion: This unique method is projected to result in significant gains in the long run. However, due to a lack of understanding of potential adverse body reactions to these novel strategies, caution must be exercised. Analyzing the biocompatibility of these nanomaterials carefully, particularly in terms of biokinetics and the problems that could arise from long-term retention of nonbiodegradable inorganic nanomaterials, is required.
Keywords
Reactive oxygen species, nanomaterial, oxidative stress, antioxidant
First Page
218
Last Page
235
Recommended Citation
FLORES, DAVID GONZALEZ; ESPINO, JAVIER; and PARIENTE, JOSE A.
(2023)
"Antioxidant potential of nanomaterials,"
Turkish Journal of Biology: Vol. 47:
No.
4, Article 2.
https://doi.org/10.55730/1300-0152.2658
Available at:
https://journals.tubitak.gov.tr/biology/vol47/iss4/2