Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.
Anthemis aciphylla, anti-inflammatory activity, carrageenin, paw edema, cotton pellet
ÖZKAYNAK, SİNEM; KOLATAN, HATİCE EFSUN; YILMAZ, OSMAN; and KIVÇAK, BİJEN
"Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.,"
Turkish Journal of Biology: Vol. 35:
6, Article 14.
Available at: https://journals.tubitak.gov.tr/biology/vol35/iss6/14