Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.

Authors

SİNEM ÖZKAYNAK
HATİCE EFSUN KOLATAN
OSMAN YILMAZ
BİJEN KIVÇAK

Abstract

Ethanolic (EEAA) and sesquiterpene lactone (SEAA) extracts of the aerial parts of Anthemis aciphylla var. aciphylla Boiss. (Asteraceae) were evaluated for anti-inflammatory activity on carrageenin-induced paw edema (acute model) and cotton pellet-induced granuloma (chronic model) in rats. In carrageenin-induced paw edema, EEAA and SEAA at intraperitoneal doses of 50, 100, and 200 mg/kg dose-dependently inhibited the paw edema. In cotton pellet-induced granuloma, the oral administration of EEAA and SEAA at 50, 100, and 200 mg/kg dosages was also found to significantly inhibit granuloma tissue formation.

DOI

10.3906/biy-1006-15

Keywords

Anthemis aciphylla, anti-inflammatory activity, carrageenin, paw edema, cotton pellet

First Page

757

Last Page

762

Recommended Citation

ÖZKAYNAK, SİNEM; KOLATAN, HATİCE EFSUN; YILMAZ, OSMAN; and KIVÇAK, BİJEN (2011) "Anti-inflammatory activity of Anthemis aciphylla var. aciphylla Boiss.," Turkish Journal of Biology: Vol. 35: No. 6, Article 14. https://doi.org/10.3906/biy-1006-15
Available at: https://journals.tubitak.gov.tr/biology/vol35/iss6/14