Turkish Journal of Biology
DOI
-
Abstract
Some new transition metal complexes of ciprofloxacin-imines derived from ciprofloxacin and p-substituted anilines were synthesized and characterized on the basis of physical properties, conductance measurements, elemental analysis, UV/Vis., infrared and nuclear magnetic resonance spectroscopy. These ligands as well as their metal complexes were also evaluated for their antibacterial activity against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus, Salmonella typhae, and E. coli. It was found that metal complexes are more antibacterial as compared to uncomplexed ligands. The present study was carried out in search of a target antibiotic instead of a broad spectrum one.
Keywords
Ciprofloxacin imines, coordination compounds, antibacterial activity
First Page
67
Last Page
72
Recommended Citation
IMRAN, MUHAMMAD; IQBAL, JAVED; IQBAL, SHAHID; and IJAZ, NAZIA (2007) "In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)," Turkish Journal of Biology: Vol. 31: No. 2, Article 2. Available at: https://journals.tubitak.gov.tr/biology/vol31/iss2/2
