Antimicrobial Effects of Verbascum georgicum Bentham Extract

Authors

MERYEM ŞENGÜL
HATİCE ÖĞÜTÇÜ
AHMET ADIGÜZEL
FİKRETTİN ŞAHİN
AYŞE AYDAN KARA
İSA KARAMAN
MEDİNE GÜLLÜCE

DOI

-

Abstract

The methanol extract of Verbascum georgicum Bentham (Scrophulariaceae) was investigated for its in-vitro antimicrobial properties. A total of 143 microorganisms belonging to 56 bacteria and 4 fungi and a yeast species were studied using the disk-diffusion method and microdilution assays. The results indicated that the methanol extract of V. geopgicum had an inhibitory effect on the growth of all Candida albicans isolates and 17 strains in 10 different species of bacteria, namely Bacillus amyloliquefaciens, B. subtilis, B. cereus, B. pumilus, B. megaterium, B. lentimorbus, B. licheniformis, Pseudomonas putida, P. syringae and Escherichia coli, at different concentrations ranging from 37.5 to 300 µg/ml. However, it did not show antifungal activity against the isolates of the 4 fungal species tested. Thus, the results suggest that V. georgicum extract possesses compounds with antimicrobial properties that might be utilized for developing new drugs.

Keywords

Verbascum georgicum, Antimicrobial activity, Medicinal plant

First Page

105

Last Page

110

Recommended Citation

ŞENGÜL, MERYEM; ÖĞÜTÇÜ, HATİCE; ADIGÜZEL, AHMET; ŞAHİN, FİKRETTİN; KARA, AYŞE AYDAN; KARAMAN, İSA; and GÜLLÜCE, MEDİNE (2005) "Antimicrobial Effects of Verbascum georgicum Bentham Extract," Turkish Journal of Biology: Vol. 29: No. 2, Article 4. Available at: https://journals.tubitak.gov.tr/biology/vol29/iss2/4