Authors: Ayla ÖZCAN, Ahmet MENGİ
Abstract: In this study, some blood, liver and kidney parameters of rats which were given alcohol orally were investigated at the end of 1st, 7th, 14th and 21st days. Forty male Wistar Albino rats (mean 196 g), 20 wk of age, were used as materials. Serum AST and \gamma-GT activities at the end of 1st day were significantly different between control and experimental groups from 40 rats studied. At the end of 7th, 14th and 21st days, the difference between two groups for AST and \gamma-GT activities in serum and liver were significant (p<0.01), but kidney enzyme levels were insignificant. ALT activity significantly increased in serum, at the end of 1st, 7th, 14th and 21st days liver and kidney of experimental group rats (p<0.01). While serum total cholesterol and total lipid levels were insignificantly different between control and experimental groups at the end of 1st and 7th days, they significantly increased in experimental group at the end of 14th and 21st days (p<0.01).
Keywords: Ethanol, Rat, Biochemical parameters
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