Estimating allele frequencies of some hereditary diseases in Holstein cattlereared in Burdur Province, Turkey


Abstract: The economics of dairy cattle breeding around the world has been significantly affected by the autosomal recessive hereditary diseases of bovine leukocyte adhesion deficiency (BLAD), factor XI deficiency (FXID), bovine citrullinemia (BC), and deficiency of uridine monophosphate synthase (DUMPS). The aim of this study was to determine BLAD, FXID, BC, and DUMPS alleles in Holstein cattle raised in Burdur Province in Turkey. This study involved taking blood samples randomly from 500 head of Holstein cattle at various dairy farms in different towns in Burdur Province. Polymerase chain reaction and restriction fragment length polymorphism (PCR-RFLP) analysis was employed to identify cows with these diseases. The results showed that the percentages of carrier animals for BLAD and FXID were 2% and 1.8%, respectively, while no DUMPS or BC was found in the study population. This is the first study on BLAD, FXID, BC, and DUMPS in Holstein cattle raised in Burdur Province in Turkey.

Keywords: Cattle, BLAD, FXID, BC, DUMPS

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