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Turkish Journal of Medical Sciences

Abstract

Background and study aim: The aim of the study is to demonstrate the effectiveness of different scoring systems and inflammatorymarkers in predicting the severity, local complications, pancreatic necrosis, and mortality of acute pancreatitis (AP).

Materials and methods: The data of 357 patients whom the severity of pancreatitis was classified according to the Revised AtlantaClassification System diagnosed with AP were retrospectively examined. Also The APACHE II, BISAP, mCTSI, and Ranson scores ofall patients were calculated. After determining the cut-off values for scoring systems and inflammatory markers with ROC analysis,comparison for AP severity, local complication, necrosis, and mortality.

Results: In the study, 2.8% of patients had severe pancreatitis. It was found that the risk of developing local complications increased 2.82times in cases with an 48th-h CRP value >192 mg/L compared to those below this threshold, and 48.96 times in cases with an mCTSIscore >2 compared to ≤ 2 cases. It was found that having a Ranson score >4 increased the risk of mortality by 9.07 times compared tohaving a score of ≤4 (p = 0.038). It was observed that having a BISAP >2 increased the risk of severe AP by 11.79 times compared to ≤2.In cases where the 48th-h NLR value was >13.33, the risk of severe AP was found to have increased by 5.85 times.

Conclusion: Although the superiority of scoring systems could not be demonstrated in our study, CRP and MCTSI for localcomplications, BISAP for severity and Ranson score for mortality were the determining variables.

Author ORCID Identifier

AHMET AKTAŞ: 0000-0002-5882-0082

DENİZ SIĞIRLI: 0000-0002-4006-3263

PINAR TAŞAR: 0000-0002-2378-0666

SADIK KILIÇTURGAY: 0000-0002-2427-8344

DOI

10.55730/1300-0144.5989

Keywords

Acute pancreatitis, laboratory parameters, prognosis, scoring systems

First Page

451

Last Page

460

Publisher

Scientific and Technological Research Council of Türkiye (TUBITAK)

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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