Overactive Bladder Syndrome and Detrusor Overactivity: Is There a Strong Relation between the Symptoms and Urodynamic Findings?


Abstract: Aim: Overactive bladder (OAB) and detrusor overactivity (DO) may interfere because one may cause the other. Not all patients with OAB have DO, neither do all patients with DO have OAB. In our study the correlation between OAB symptoms and DO was investigated. Materials and Methods: In the present study, 190 patients with OAB and/or DO were investigated. Patients were divided into 3 groups: OAB with DO group (group 1, n = 63), DO without OAB group (group 2, n = 34), and OAB without DO group (group 3, n = 93). The symptoms and urodynamic findings of the patients from these 3 groups were compared between each other with the independent t-test and Mann-Whitney U test. For prediction of DO, a logistic regression model was performed. Results: There were 156 patients having OAB syndrome. Of them, 63 patients (40%) had involuntary contractions on urodynamic studies. DO was present in 97 patients; among these patients, OAB was observed in 63 (65%) patients. Nocturia and urge incontinence (UI) were the significant predictors of DO in female and male patients, respectively. Conclusions: There is not an exact correlation between OAB symptoms and DO. In our study nocturia and UI were the predicting symptoms for DO in female and male patients, respectively. But to make exact comments, these results must be verified by epidemiologic studies.

Keywords: Overactive bladder syndrome, detrusor overactivity, nocturia, urgency, urge urinary incontinence

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