Authors: İSMAİL MERAL, BURHANETTİN BAYDAŞ, FAHRİ BAYIROĞLU, HAMDİ UYSAL
Abstract: This experiment was carried out to evaluate the role of vitamin E in decreasing the toxic effect of digoxin. Electrocardiographic recordings of New Zealand rabbits which were treated with digoxin-only or digoxin+vitamin E were used. Recordings were obtained before and 24 hours after treatments. It was found that digoxin-only treatment caused a sinusoidal tachicardia without changing the durations or amplitudes of any wave on the trace. However, digoxin+vitamin E treatment did not produce any increase in heart rate. It was concluded that vitamin E injection along with digoxin injection might lower the toxic effect of digoxin. More studies are needed to convince these findings.
Keywords: Digoxin, Vitamin E, Rabbits, Electrocardiogram.
Full Text: PDF