The Use of Laboratory Findings in the Diagnosis of CEH-Pyometra Complex in the Bitch


Abstract: The aim of this study was to research the effects of ultrasonography, vaginal cytology, a serum biochemical profile, complete blood count and blood gas analysis in 18 bitches in the diagnosis of cystic endometrial hyperplasia (CEH)-pyometra complex. In transabdomimal ultrasonography, it was observed the the majority of anechongenic areas differed with the thickness of the uterine wall. Usually basal-parabasal type of cells appeared in vaginal cytologic examination, invasion of neutrophyl leucocytes and in some cases degenerative cell changes proved inflammatory changes. In bitches with CEH-pyometra complex there was a very significant increase in AST (Aspartate aminotransferase) and decrease in the ALT (Alanine aminotransferase). White blood cell (WBC) levels were higher than 12x10 3 xmm 3 . MCV count results showed that 93.3% of the cases were higher than the normal concentrations. The concentration of creatine and urea were found to be lower than the normal levels. Creatine concentrations were higher only in 30.7% of the animals and the GGT (Gama glutamyltransferase) levels to be higher in 33.3% of the animals. In 84.06% of the bitches with pyometra, serum albumin levels found to be lower than 4.1 g/dl. For all of the bitches, lactate dehydrogenase (LDH) levels were higher than 143-171 u/l. Triglycerides were found to be higher than 0.2-1.8 mmol/l in 70% of the bitches. It can be assumed that the normal level of serum alkaline phosphatase (ALP) shows the severity of low renal failure in 58.33% of the bitches. In the blood gas analysis it was determined that PO 2 levels in 90% of the bitches and HCO 3 levels in 60% of the bitches with pyometra were lower than 85-95 mmHg and 17-25 mmol/l respectively.

Keywords: Pyometra, bitch, laboratory diagnosis, vaginal cytology.

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