Authors: ALİ KUMANDAŞ, ERTUĞRUL ELMA
Abstract: Seven healthy Angora goats were used to compare the effects of isoflurane and sevoflurane on the cardiovascular and respiratory systems during anesthesia periods. Once anesthesia was induced with propofol at 5.1 ± 0.9 mg/kg, it was maintained with isoflurane at 1%-3% in the first treatment period and sevoflurane at 2%-4% in the second treatment period after a 15-day interval. Heart rates measured immediately after anesthesia induction and 5 min later were found to be statistically significant between anesthetic groups (P < 0.05). Mean blood pressure in the isoflurane group decreased (75.7 ± 7.2 to 59.8 ± 9.8 mmHg) (P < 0.05) throughout the anesthesia period. It was determined that respiratory rate in sevoflurane treatment was lower than that in isoflurane treatment. In terms of time to stand up, sevoflurane-administered animals recovered significantly faster than animals intubated with isoflurane anesthesia (13.1 ± 4.4 and 25.0 ± 8.6 min) (P < 0.05). According to cardiopulmonary values, the respiratory rate was lower in the sevoflurane-applied animals compared to that of those receiving isoflurane anesthesia, although the difference was not statistically significant, and hypercapnia were not observed in either group. Consequently, it was determined that in the Angora goat, propofol-sevoflurane anesthesia exerts lower pressure on the cardiovascular system than isoflurane anesthesia. At the same time, recovery from sevoflurane anesthesia was shorter, and therefore it can be preferred to other anesthesia agents for routine anesthesia.
Keywords: Sevoflurane, isoflurane, anesthesia, cardiovascular system, respiratory system, Angora goat
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