Authors: TARIK EL-SAYED ALI, SALAH ABDEL-AGHFAAR ABDEL-AZIZ, HAFEZ METWALI EL-SHAAER, FATEN ISMAIL HANAFY, ALI ZAKY EL-FAUOMY
Abstract: Some new 4-oxo-4H-chromone derivatives bearing nitrogen heterocyclic systems were achieved by treatment of 3-[(4-aminophenylimino) methyl]-6-chloro-4-oxo-4H-chromene (2) with some aldehydes, cyclic oxygen, and halogen compounds, followed by heterocyclization. Significant antifungal activities were observed for some of the prepared compounds. Structures of all products were confirmed by elemental analysis, IR, ^1H-NMR, and mass spectra.
Keywords: Chromone, nitrogen heterocycles, antifungal activity
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