Authors: JURGEN KRAUSS, SANDRA KALKBRENNER, ANGELA SCHUSTER, ANNE OBAINOKE, FRANZ BRACHER
Abstract: Bengazole A and bengazole B are 2 representatives out of a large family of marine metabolites isolated from a Jaspis sponge and display potent anti-fungal and anthelmintic activity as well as modest cytotoxic activity. This paper reports a short and efficient synthesis and microbiological evaluation of some new bengazole analogues.
Keywords: Bengazole, lithiation, antimicrobial activity, cytotoxicity
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