Authors: HANY MOHAMED HASSANIN, MAGDY AHMED IBRAHIM, YOUSSEF ABDEL-SALAM ALNAMER
Abstract: Chlorination, bromination, and condensation reactions of 3-(1-ethy1-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)-3-oxopropanoic acid (3) were studied. Some novel 4-hydroxyquinolin-2(1H)-ones and pyrano[3,2-c]quinolin-2(1H)-ones were also prepared. The structures of the novel compounds were established by elemental analyses and spectral data. All the products were also screened in vitro for their antimicrobial activity.
Keywords: \beta-Ketoacid, 4-hydroxyquinolin-2(1H)-one, pyrano[3,2-c]quinolinone, condensation reactions
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