Authors: BEHZAD MOHAMMADI, SAYYED MOHAMMAD HOSSEINI JAMKARANI, TAGHI A. KAMALI, MAHMOUD NASROLLAHZADEH, ALI MOHAJERI
Abstract: An efficient one-pot method for the synthesis of 1,4-dihydropyridines from \beta-dicarbonyl compounds, aldehyde, and ammonium acetate is reported using sulfonic acid-functionalized silica at 90 °C under solvent-free conditions with good to excellent yields. The catalyst is easily prepared, stable (up to 300 °C), reusable, and efficiently used under reaction conditions.
Keywords: 1,4-Dihydropyridine, \beta-dicarbonyl compounds, solid acid, SiO_2-R-SO_3H, heterogeneous catalyst
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