Authors: MALEK TAHER MAGHSOODLOU, SAYYED MOSTAFA HABIBI-KHORASSANI, REZA HEYDARI, NOUROLLAH HAZERI, SEYED SAJAD SAJADIKHAH, MOHSEN ROSTAMIZADEH, LEILA KEISHAMS
Abstract: An efficient green protocol is described for the preparation of \alpha -amino phosphonates, employing a one-pot three-component condensation reaction between aldehydes, amines, and trialkyl phosphites in the presence of PPA-SiO_2 under solvent-free conditions at 80 °C. The present procedure offer advantages such as high to excellent yields, short reaction time, inexpensiveness, recovery, and reusability of catalyst.
Keywords: \alpha -Amino phosphonates; PPA-SiO_2; heterogeneous catalyst; trialkyl phosphites
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