Authors: DEQUN SUN
Abstract: An efficient and new method was developed to prepare the dopa analogue 11 in natural pepticinnamin via catalytic hydrogenation of dehydroamino acids (DDAA) with a good yield and ee. Product 11 is a key intermediate towards the total synthesis of pepticinnamin E and its analogues.
Keywords: Synthesis; dopa analogue; enantioselective hydrogenation; dehydroamino acid.
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